CBD might help with fatty liver by reducing inflammation and acting as an antioxidant, but some evidence suggests it could raise liver enzymes.
CBD, or cannabidiol, is a nonpsychoactive compound in cannabis known for its therapeutic effects like reducing inflammation and anxiety.
Research suggests that CBD is generally well-tolerated and may offer protective effects for the liver. However, high doses may interact with certain medications and potentially affect liver enzymes. Here’s what we know so far.
Research suggests that CBD might help reduce fatty liver in both alcohol-related and nonalcoholic fatty liver disease.
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The protective effects remained, even when considering factors like obesity and diabetes.
The study proposes that CBD, which acts on anti-inflammatory CB-2 receptors, may offer defenses against NAFLD, but further research is needed for a better understanding of these effects.
CBD may also offer benefits for alcohol-related fatty liver disease. A study involving mice looked at whether CBD can protect the liver from damage caused by a combination of excessive alcohol consumption and a high fat, high cholesterol diet. The findings show that CBD helps prevent fat accumulation and oxidative stress in the liver.
CBD achieves this by reducing inflammation and blocking specific pathways related to liver damage.
Here are some potential ways in which CBD may influence factors related to liver fat accumulation:
CBD is generally considered safe. However, certain individuals should use caution or avoid using CBD. This includes pregnant or breastfeeding people, as the effects of CBD on fetal development and infants aren’t well-established.
Other potential side effects include:
Some
Elevated liver enzymes, including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), indicate liver stress or damage, as these enzymes are released into the bloodstream when the liver is inflamed or impaired.
However, it’s important to note that observing a link doesn’t definitively establish that CBD directly causes liver damage.
CBD can interact with drugs processed by the liver’s cytochrome P450 enzyme system, affecting their metabolism and potentially resulting in adverse effects.
Some examples of drugs that may be affected include:
CBD is a non-psychoactive compound found in cannabis, known for its potential therapeutic benefits. Some studies suggest CBD might benefit liver health due to its anti-inflammatory and antioxidant properties. However, there are concerns about potential side effects, including elevated liver enzymes and drug interactions.
If you have a liver condition and are thinking about using CBD, it’s a good idea to talk with your doctor first. They can make sure it’s safe for you and keep an eye on any potential issues.
Last medically reviewed on March 14, 2024
Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
Current Version
Mar 14, 2024
Written By
Traci Pedersen
Edited By
Ari Howard
Medically Reviewed By
Eloise Theisen, RN, MSN, AGPCNP-BC
Copy Edited By
Nastassja Myer
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