COMP360 psilocybin treatment in TRD with antidepressants – COMPASS Pathways

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COMP360 psilocybin treatment in TRD
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About us
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We conducted an exploratory study of investigational COMP360 psilocybin treatment in combination with SSRI use. The open-label study involved 19 patients taking SSRI therapy alongside 25mg COMP360 psilocybin treatment. The results showed comparable treatment outcomes to those seen in patients in our phase 2b trial, where patients were withdrawn from their SSRI before they received COMP360 psilocybin treatment.
Press release
Dr Guy Goodwin, Chief Medical Officer, Compass Pathways
Watch the video to hear Dr Goodwin talk about the study and what it could mean for future clinical trials using our investigational COMP360 psilocybin treatment.
“This study is an important contribution to our knowledge and has significant implications for clinical research with psychedelics.
Pragmatically, the findings suggest that future clinical trials of psilocybin treatment may be able to include patients who have great difficulty coming off SSRI antidepressants and that, ultimately, such patients could be eligible for any psilocybin treatments that may become approved.”
Dr David Feifel, Professor Emeritus of Psychiatry and Principal Investigator on the trial’s site at Kadima Neuropsychiatry Institute
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